Centrifuges are core equipment in the production process of biological products. Through in-depth analysis of industry demands and continuous technological research and development, our company has successfully developed and trial-produced centrifuges that fully meet pharmaceutical CIP (Clean-in-Place) and SIP (Sterilize-in-Place) requirements, breaking the monopoly of foreign brands.
Applications of Disc Centrifuge
Vaccine Preparation
Efficiently separate viral particles from cell debris to guarantee the purity and activity of vaccines.
Efficiently separate viral particles from cell debris to guarantee the purity and activity of vaccines.
API Clarification
Effectively remove bacterial cells and impurities from fermentation broth, improving product purity and yield.
Effectively remove bacterial cells and impurities from fermentation broth, improving product purity and yield.
Enzyme Extraction
Gently separate intracellular enzymes from cell debris while maintaining enzyme activity and recovery efficiency.
Gently separate intracellular enzymes from cell debris while maintaining enzyme activity and recovery efficiency.
Antibody Production
Accurately recover target antibodies and eliminate host proteins and contaminants to enhance product yield.
Accurately recover target antibodies and eliminate host proteins and contaminants to enhance product yield.
Product Features
Automatic Feeding Control
Adopts a fully closed automatic feeding design. Equipped with high-precision regulating valves and real-time flow monitoring, it realizes stable material conveying, effectively protects active substances such as cells and proteins, and increases product yield. It is ideal for separation and purification of sensitive materials including biological products and fermentation broth.
Precision Drum Assembly
High-precision disc stack with full laser welding. The disc gaps are optimized based on fluid dynamics to form stable laminar flow. During high-speed rotation, inclusion bodies, cell debris and other contaminants are rapidly separated from the clarified liquid, boosting overall separation efficiency and operational stability.
Purified Water Supply Guarantee
Equipped with a standard built-in purified water storage tank to provide cooling water and lubrication with stable pressure for mechanical seals continuously. It can maintain water supply for a certain period even under sudden water cutoff conditions, preventing dry friction of mechanical seals, extending equipment service life and ensuring production safety.
Aseptic Isolation Protection
Comes with a standard aseptic isolation tank. The overflow water from slag discharge effectively isolates ambient air and prevents microbial contamination from entering the separation system, maintaining an aseptic production environment throughout the process. It is applicable to high-standard aseptic production such as vaccines and insulin.
Integrated SIP Module & Aseptic Maintenance
The centrifuge is integrated with an SIP sterilization system to perform comprehensive and verifiable online cleaning and sterilization before and after production. It maintains internal sterility of the equipment, complies with GMP regulations, and supports continuous aseptic production.
Real-time Temperature Monitoring
Multiple temperature sensors are installed to monitor and feedback the temperature of feeding, separation and discharging processes in real time. This ensures materials are always kept within the optimal temperature range, avoids damage to active ingredients, and improves product consistency and safety.
On-site Real-time Sampling & Testing
The equipment supports aseptic sampling during production. Operators can monitor key indicators such as material status, clarity and bacterial concentration in real time, and adjust process parameters timely to stabilize product quality.
Complete GMP Validation Documentation
Adopting a risk-oriented philosophy, we implement validation and change management throughout design, manufacturing, commissioning and operation. A full set of validation documents including VP, CA, FMEA, DQ, IQ, OQ, PQ and VSR are provided to ensure controllable process performance, authentic, complete and traceable data. This enables products to enter the international market faster and more steadily.
