News I Sino Bioengineering

In the landscape of modern oncology, antibody-drug conjugates (ADCs) have evolved from an ingenious laboratory concept into one of the most dynamic and promising sector……

In the biopharmaceutical industry, there is a time-honored maxim: “The process is the product.” This tenet is not only a widely recognized industry consensus but also……

The formation of protein particles in drug substance (DS) and drug product (DP) manufacturing of antibodies and recombinant proteins has been widely reported. Typical manifestations……

With the advancement of the biopharmaceutical industry, an increasing number of high-concentration monoclonal antibody (mAb) formulations have been approved for marketing. Since 199……

In recent years, substantial progress has been made in the formulation development and stability optimization of liquid biological products. This article systematically summarizes t……

Against the backdrop of a booming biopharmaceutical industry, prefilled syringes have become the preferred delivery system for innovative formulations including monoclonal antibody ……

If mRNA therapeutics are likened to confidential biological dispatches destined for the interior of cells, lipid nanoparticles (LNPs) act as elite escorts that navigate a host of bi……

Lipid nanoparticles (LNPs) and liposomes are two of the most prevalent yet frequently confused concepts in lipid drug delivery. Many mistakenly equate the two or regard LNPs merely ……

Particle size stands as a decisive critical parameter throughout the delivery journey of mRNA-LNP therapeutics. Unlike mRNA molecules that carry genetic information or ionizable lip……

Driven by the rapid advancement of gene therapy, cell therapy and mRNA vaccines, the industry demand for plasmid DNA (pDNA) has surged. Developing robust plasmid manufacturing proce……

mRNA vaccines feature rapid production and superior process versatility, granting them unparalleled advantages in responding to public health emergencies. The successful deployment ……

In 2026, with the full implementation of EU GMP Annex 1 and the revised PDA Technical Report No. 26, the global sterile pharmaceutical manufacturing industry has undergone a compreh……

I. Design Philosophy of Cell Culture Media: Precision Bionics at the Microscale Inside living organisms, cells are sustained by the circulatory system, which delivers a constant t……

Cell culture medium serves as the fundamental substrate for in vitro cell growth. Its selection directly impacts cell status, experimental reproducibility and the credibility of res……

Overview Cell culture media are artificially formulated solutions that simulate the in vivo physiological environment of cells, supplying essential nutrients to sustain cell survival……

In industries including biotechnology, biopharmaceuticals, bioenergy, food and feed production, efficient recovery of intracellular compounds is a core link running through R&D ……