News I Sino Bioengineering

Rabies is an acute infectious disease caused by the Rabies virus (RABV), commonly transmitted through bites or scratches from infected animals, mainly including dogs, cats, bats and ……

The in-use stability study simulates the actual clinical application scenarios of biological products and investigates critical quality attributes including physical, chemical and bi……

Preface With the rapid advancement of the biopharmaceutical industry, the demand for the development of high-concentration protein formulations (HCPF, >100 mg/ml) continues to gro……

Cell culture process scale-up is a critical step in the production of therapeutic proteins. To meet market demand for therapeutic proteins, production must be scaled up to commercial……

As a vital component of modern pharmaceutical industry, biological products play an essential role in disease treatment and public health protection. The biological product industry ……

Bispecific antibodies (bsAbs) represent a promising class of biotherapeutics. Accordingly, downstream processing of such antibodies is critical to ensuring the production of high-pur……

In the biopharmaceutical industry, Chinese Hamster Ovary (CHO) cells have emerged as the gold-standard expression system for recombinant protein production. The conventional fed-batc……

Since the first monoclonal antibody drug was approved in 1986, the research and development of antibody drugs have flourished. Up to now, antibody drugs have become an important part……

With the continuous advancement of biomedical technologies, multispecific antibodies (MSAs) have demonstrated enormous potential in the therapeutic field. Capable of targeting multip……

Virus-like Particles (VLPs) are unique biomaterials that structurally mimic the morphology and configuration of native viruses, yet they contain no viral genetic material such as DNA……

In the design and operation of bioreactors, hydrodynamic effects are consistently critical factors. Depending on the application area, their impacts can be divided into two categorie……

Over the past three decades, significant progress has been made in the production of therapeutic proteins in the biopharmaceutical industry, driving sustained growth in the market. I……

In recent years, the application of microbial cell factories in the biosynthesis of natural products has gradually become an important direction in biomanufacturing. Compared with tr……

HEK293 cells were originally isolated by Alex Van der Eb in the 1970s and subsequently transformed by Frank Graham using sheared fragments of adenovirus type 5 (Ad5) DNA. Owing to th……

Perfusion technology is widely applied in bioengineering, chemical engineering and other fields. The key fundamentals are introduced in detail as follows. Necessity of Perfusion Pain……

With the widespread adoption of precision medicine, an increasing number of therapeutic biologics such as bispecific antibodies, antibody-drug conjugates (ADCs), and CAR-T cell thera……